1. Home
  2. Virginia
  3. Wytheville Hotels
  4. Hotels on E Main St
  5. Best Western

Best Western Hotels Near E Main St


Best Western Wytheville Inn
355 Nye Rd
Wytheville, VA 24382
Check prices and availability
Hotel Brands Near E Main St
Ascend Collection
Comfort Suites
Country Inns By Carlson
Fairfield Inn by Marriott
Ramada International
Rodeway Inn
Hampton Inn
Super 8
Sleep Inns
Best Western
La Quinta Inns & Suites
Red Roof Inns
Travelodge
Quality Inns
Days Inn
Holiday Inn Express
Econo Lodge
Wytheville Hotels By Street Names
Hotels on East Main Street in Wytheville
Hotels on Peppers Ferry Road in Wytheville
Hotels on Nye Circle in Wytheville
Hotels on Lithia Road in Wytheville
Hotels on Marriott Way in Wytheville
Hotels on Malin Drive in Wytheville
Hotels on Lithia Rd in Wytheville
Hotels on Chapman Road in Wytheville
Hotels on Peppers Ferry Rd in Wytheville
Hotels on Peppers Ferry in Wytheville
Hotels on Nye Road in Wytheville
Hotels on Malin Dr in Wytheville
Hotels on Malin Dr, I-81 and I-77 Exit 73 in Wytheville
Hotels on Nye Rd in Wytheville
Hotels on Nye Cir in Wytheville
Hotels on E Main St in Wytheville
Hotels on Holston Rd in Wytheville
Hotels on E Lee Hwy in Wytheville
Book Hotels Online
or call 1-866-226-8756
Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.